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Opposing regulatory roles of phosphorylation and acetylation in DNA mispair processing by thymine DNA glycosylase

CpG dinucleotides are mutational hotspots associated with cancer and genetic diseases. Thymine DNA glycosylase (TDG) plays an integral role in CpG maintenance by excising mispaired thymine and uracil in a CpG context and also participates in transcriptional regulation via gene-specific CpG demethyla...

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Detalles Bibliográficos
Autores principales:	Mohan, Ryan D., Litchfield, David W., Torchia, Joseph, Tini, Marc
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2010
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831317/ https://www.ncbi.nlm.nih.gov/pubmed/19966277 http://dx.doi.org/10.1093/nar/gkp1097

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