Pharmacogenetics of asthma in children

Allergic diseases such as bronchial asthma and atopic dermatitis develop by a combination of genetic and environmental factors. Several candidate causative genes of asthma and atopy have been reported as the genetic factors. The clinical features of patients and causes of diseases vary. Therefore, p...

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Detalles Bibliográficos
Autores principales: Kondo, Naomi, Matsui, Eiko, Nishimura, Akane, Kaneko, Hideo
Formato: Texto
Lenguaje:English
Publicado: The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 2010
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831608/
https://www.ncbi.nlm.nih.gov/pubmed/20224673
http://dx.doi.org/10.4168/aair.2010.2.1.14
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author Kondo, Naomi
Matsui, Eiko
Nishimura, Akane
Kaneko, Hideo
author_facet Kondo, Naomi
Matsui, Eiko
Nishimura, Akane
Kaneko, Hideo
author_sort Kondo, Naomi
collection PubMed
description Allergic diseases such as bronchial asthma and atopic dermatitis develop by a combination of genetic and environmental factors. Several candidate causative genes of asthma and atopy have been reported as the genetic factors. The clinical features of patients and causes of diseases vary. Therefore, personalized medicine (tailor-made medicine) is necessary for the improvement of quality of life (QOL) and for asthma cure. Pharmacogenetics is very important for personalized medicine. Here, we present the genetics and pharmacogenetics of asthma in children. Finally, we show the guideline for personalized medicine for asthma, particularly in childhood, including the pharmacogenetics of anti-asthmatic drugs, preliminarily produced by the authors.
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spelling pubmed-28316082010-03-11 Pharmacogenetics of asthma in children Kondo, Naomi Matsui, Eiko Nishimura, Akane Kaneko, Hideo Allergy Asthma Immunol Res Review Allergic diseases such as bronchial asthma and atopic dermatitis develop by a combination of genetic and environmental factors. Several candidate causative genes of asthma and atopy have been reported as the genetic factors. The clinical features of patients and causes of diseases vary. Therefore, personalized medicine (tailor-made medicine) is necessary for the improvement of quality of life (QOL) and for asthma cure. Pharmacogenetics is very important for personalized medicine. Here, we present the genetics and pharmacogenetics of asthma in children. Finally, we show the guideline for personalized medicine for asthma, particularly in childhood, including the pharmacogenetics of anti-asthmatic drugs, preliminarily produced by the authors. The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 2010-01 2009-12-30 /pmc/articles/PMC2831608/ /pubmed/20224673 http://dx.doi.org/10.4168/aair.2010.2.1.14 Text en Copyright © 2010 The Korean Academy of Asthma, Allergy and Clinical Immunology • The Korean Academy of Pediatric Allergy and Respiratory Disease http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Kondo, Naomi
Matsui, Eiko
Nishimura, Akane
Kaneko, Hideo
Pharmacogenetics of asthma in children
title Pharmacogenetics of asthma in children
title_full Pharmacogenetics of asthma in children
title_fullStr Pharmacogenetics of asthma in children
title_full_unstemmed Pharmacogenetics of asthma in children
title_short Pharmacogenetics of asthma in children
title_sort pharmacogenetics of asthma in children
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831608/
https://www.ncbi.nlm.nih.gov/pubmed/20224673
http://dx.doi.org/10.4168/aair.2010.2.1.14
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AT matsuieiko pharmacogeneticsofasthmainchildren
AT nishimuraakane pharmacogeneticsofasthmainchildren
AT kanekohideo pharmacogeneticsofasthmainchildren

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