Methylnaltrexone Potentiates the Anti-Angiogenic Effects of mTOR Inhibitors

BACKGROUND: Recent cancer therapies include drugs that target both tumor growth and angiogenesis including mammalian target of rapamycin (mTOR) inhibitors. Since mTOR inhibitor therapy is associated with significant side effects, we examined potential agents that can reduce the therapeutic dose. MET...

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Detalles Bibliográficos
Autores principales: Singleton, Patrick A, Mambetsariev, Nurbek, Lennon, Frances E, Mathew, Biji, Siegler, Jessica H, Moreno-Vinasco, Liliana, Salgia, Ravi, Moss, Jonathan, Garcia, Joe GN
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831839/
https://www.ncbi.nlm.nih.gov/pubmed/20298531
http://dx.doi.org/10.1186/2040-2384-2-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831839/
https://www.ncbi.nlm.nih.gov/pubmed/20298531
http://dx.doi.org/10.1186/2040-2384-2-5

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