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Retrotransposition and mutation events yield Rap1 GTPases with differential signalling capacity
BACKGROUND: Retrotransposition of mRNA transcripts gives occasionally rise to functional retrogenes. Through acquiring tempero-spatial expression patterns distinct from their parental genes and/or functional mutations in their coding sequences, such retrogenes may in principle reshape signalling net...
Autores principales: | Zemojtel, Tomasz, Duchniewicz, Marlena, Zhang, Zhongchun, Paluch, Taisa, Luz, Hannes, Penzkofer, Tobias, Scheele, Jürgen S, Zwartkruis, Fried JT |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831893/ https://www.ncbi.nlm.nih.gov/pubmed/20170508 http://dx.doi.org/10.1186/1471-2148-10-55 |
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