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Development of HIF-1 inhibitors for cancer therapy

Intratumour hypoxia has long been considered a driving force of tumour progression and a negative prognostic factor in human cancers. The discovery of hypoxia inducible factors (HIFs), which mediate transcriptional responses to changes in oxygen levels, has renewed enthusiasm for the discovery and d...

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Detalles Bibliográficos
Autores principales:	Onnis, Barbara, Rapisarda, Annamaria, Melillo, Giovanni
Formato:	Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Ltd 2009
Materias:	Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2832082/ https://www.ncbi.nlm.nih.gov/pubmed/19674190 http://dx.doi.org/10.1111/j.1582-4934.2009.00876.x

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