Limited Trafficking of a Neurotropic Virus Through Inefficient Retrograde Axonal Transport and the Type I Interferon Response

Poliovirus is an enteric virus that rarely invades the human central nervous system (CNS). To identify barriers limiting poliovirus spread from the periphery to CNS, we monitored trafficking of 10 marked viruses. After oral inoculation of susceptible mice, poliovirus was present in peripheral neuron...

Descripción completa

Detalles Bibliográficos
Autores principales: Lancaster, Karen Z., Pfeiffer, Julie K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2832671/
https://www.ncbi.nlm.nih.gov/pubmed/20221252
http://dx.doi.org/10.1371/journal.ppat.1000791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2832671/
https://www.ncbi.nlm.nih.gov/pubmed/20221252
http://dx.doi.org/10.1371/journal.ppat.1000791

Ejemplares similares