Cargando…

Fatal Transmissible Amyloid Encephalopathy: A New Type of Prion Disease Associated with Lack of Prion Protein Membrane Anchoring

Prion diseases are fatal neurodegenerative diseases of humans and animals characterized by gray matter spongiosis and accumulation of aggregated, misfolded, protease-resistant prion protein (PrPres). PrPres can be deposited in brain in an amyloid-form and/or non-amyloid form, and is derived from hos...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chesebro, Bruce, Race, Brent, Meade-White, Kimberly, LaCasse, Rachel, Race, Richard, Klingeborn, Mikael, Striebel, James, Dorward, David, McGovern, Gillian, Jeffrey, Martin
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2832701/ https://www.ncbi.nlm.nih.gov/pubmed/20221436 http://dx.doi.org/10.1371/journal.ppat.1000800

Ejemplares similares

Unusual cerebral vascular prion protein amyloid distribution in scrapie-infected transgenic mice expressing anchorless prion protein
por: Rangel, Alejandra, et al.
Publicado: (2013)

Microglia are not required for prion-induced retinal photoreceptor degeneration
por: Striebel, James F., et al.
Publicado: (2019)

Distinct patterns of spread of prion infection in brains of mice expressing anchorless or anchored forms of prion protein
por: Rangel, Alejandra, et al.
Publicado: (2014)

Strain Specific Resistance to Murine Scrapie Associated with a Naturally Occurring Human Prion Protein Polymorphism at Residue 171
por: Striebel, James F., et al.
Publicado: (2011)

Prion protein and susceptibility to kainate-induced seizures: Genetic pitfalls in the use of PrP knockout mice
por: Striebel, James F, et al.
Publicado: (2013)

Prion-induced photoreceptor degeneration begins with misfolded prion protein accumulation in cones at two distinct sites: cilia and ribbon synapses
por: Striebel, James F., et al.
Publicado: (2021)

Detection of Prion Infectivity in Fat Tissues of Scrapie-Infected Mice
por: Race, Brent, et al.
Publicado: (2008)

CD11c is not required by microglia to convey neuroprotection after prion infection
por: Carroll, James A., et al.
Publicado: (2023)

RNA-seq and network analysis reveal unique glial gene expression signatures during prion infection
por: Carroll, James A., et al.
Publicado: (2020)

Second passage experiments of chronic wasting disease in transgenic mice overexpressing human prion protein
por: Race, Brent, et al.
Publicado: (2022)

Prion Strain Differences in Accumulation of PrPSc on Neurons and Glia Are Associated with Similar Expression Profiles of Neuroinflammatory Genes: Comparison of Three Prion Strains
por: Carroll, James A., et al.
Publicado: (2016)

Levels of Abnormal Prion Protein in Deer and Elk with Chronic Wasting Disease
por: Race, Brent L., et al.
Publicado: (2007)

Inactivation of chronic wasting disease prions using sodium hypochlorite
por: Williams, Katie, et al.
Publicado: (2019)

Microglia have limited influence on early prion pathogenesis, clearance, or replication
por: Race, Brent, et al.
Publicado: (2022)

Toll-like receptor 2 confers partial neuroprotection during prion disease
por: Carroll, James A., et al.
Publicado: (2018)

Transmission studies of chronic wasting disease to transgenic mice overexpressing human prion protein using the RT-QuIC assay
por: Race, Brent, et al.
Publicado: (2019)

Familial human prion diseases associated with prion protein mutations Y226X and G131V are transmissible to transgenic mice expressing human prion protein
por: Race, Brent, et al.
Publicado: (2018)

Deletion of Kif5c Does Not Alter Prion Disease Tempo or Spread in Mouse Brain
por: Race, Brent, et al.
Publicado: (2021)

Chronic Wasting Disease Agents in Nonhuman Primates
por: Race, Brent, et al.
Publicado: (2014)

Efficacy of Wex-cide 128 disinfectant against multiple prion strains
por: Baune, Chase, et al.
Publicado: (2023)

Cellular prion protein is present in mitochondria of healthy mice
por: Faris, Robert, et al.
Publicado: (2017)

Inactivation of Prions and Amyloid Seeds with Hypochlorous Acid
por: Hughson, Andrew G., et al.
Publicado: (2016)

Prion disease induced alterations in gene expression in spleen and brain prior to clinical symptoms
por: Kim, Hyeon O, et al.
Publicado: (2008)

Innate immune responses after stimulation with Toll-like receptor agonists in ex vivo microglial cultures and an in vivo model using mice with reduced microglia
por: Carroll, James A., et al.
Publicado: (2021)

Rapid End-Point Quantitation of Prion Seeding Activity with Sensitivity Comparable to Bioassays
por: Wilham, Jason M., et al.
Publicado: (2010)

Membrane Toxicity of Abnormal Prion Protein in Adrenal Chromaffin Cells of Scrapie Infected Sheep
por: McGovern, Gillian, et al.
Publicado: (2013)

Reduced SOD2 expression does not influence prion disease course or pathology in mice
por: Foliaki, Simote T., et al.
Publicado: (2021)

Sporadic Creutzfeldt-Jakob disease prion infection of human cerebral organoids
por: Groveman, Bradley R., et al.
Publicado: (2019)

Early Generation of New PrPSc on Blood Vessels after Brain Microinjection of Scrapie in Mice
por: Chesebro, Bruce, et al.
Publicado: (2015)

Early preclinical detection of prions in the skin of prion-infected animals
por: Wang, Zerui, et al.
Publicado: (2019)

Prions by activation not amyloid
por: Wells, William A.
Publicado: (2003)

Neuron-specific expression of a hamster prion protein minigene in transgenic mice induces susceptibility to hamster scrapie agent
por: Race, Richard E., et al.
Publicado: (1995)

Publisher Correction: Early preclinical detection of prions in the skin of prion-infected animals
por: Wang, Zerui, et al.
Publicado: (2019)

Reduction of Chronic Wasting Disease Prion Seeding Activity following Digestion by Mountain Lions
por: Baune, Chase, et al.
Publicado: (2021)

PrP aggregation can be seeded by pre-formed recombinant PrP amyloid fibrils without the replication of infectious prions
por: Barron, Rona M., et al.
Publicado: (2016)

Porcine prion protein amyloid
por: Hammarström, Per, et al.
Publicado: (2015)

Altered distribution, aggregation, and protease resistance of cellular prion protein following intracranial inoculation
por: Ward, Anne, et al.
Publicado: (2019)

Intraperitoneal Infection of Wild-Type Mice with Synthetically Generated Mammalian Prion
por: Wang, Xinhe, et al.
Publicado: (2015)

Neuroinflammation, Microglia, and Cell-Association during Prion Disease
por: Carroll, James A., et al.
Publicado: (2019)

Proteomics Analysis of Amyloid and Nonamyloid Prion Disease Phenotypes Reveals Both Common and Divergent Mechanisms of Neuropathogenesis
por: Moore, Roger A., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_askd40o8kirrh8cl05srrtnbln