Immune responses to Epstein–Barr virus: molecular interactions in the virus evasion of CD8(+) T cell immunity

Persistent viruses have mechanisms for modulating the host immune responses that are essential for achieving a lifelong virus–host balance while minimizing the viral pathogenicity. Here we review some of the immune-modulating mechanisms evolved by the ubiquitous but potentially oncogenic Epstein–Bar...

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Detalles Bibliográficos
Autores principales: Rowe, Martin, Zuo, Jianmin
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2010
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2832755/
https://www.ncbi.nlm.nih.gov/pubmed/20004735
http://dx.doi.org/10.1016/j.micinf.2009.12.001
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author Rowe, Martin
Zuo, Jianmin
author_facet Rowe, Martin
Zuo, Jianmin
author_sort Rowe, Martin
collection PubMed
description Persistent viruses have mechanisms for modulating the host immune responses that are essential for achieving a lifelong virus–host balance while minimizing the viral pathogenicity. Here we review some of the immune-modulating mechanisms evolved by the ubiquitous but potentially oncogenic Epstein–Barr virus, with particular emphasis on the molecular mechanisms of genes interfering with HLA class I antigen presentation.
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spelling pubmed-28327552010-03-29 Immune responses to Epstein–Barr virus: molecular interactions in the virus evasion of CD8(+) T cell immunity Rowe, Martin Zuo, Jianmin Microbes Infect Review Persistent viruses have mechanisms for modulating the host immune responses that are essential for achieving a lifelong virus–host balance while minimizing the viral pathogenicity. Here we review some of the immune-modulating mechanisms evolved by the ubiquitous but potentially oncogenic Epstein–Barr virus, with particular emphasis on the molecular mechanisms of genes interfering with HLA class I antigen presentation. Elsevier 2010-03 /pmc/articles/PMC2832755/ /pubmed/20004735 http://dx.doi.org/10.1016/j.micinf.2009.12.001 Text en © 2010 Elsevier Masson SAS. https://creativecommons.org/licenses/by/4.0/ Open Access under CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/) license
spellingShingle Review
Rowe, Martin
Zuo, Jianmin
Immune responses to Epstein–Barr virus: molecular interactions in the virus evasion of CD8(+) T cell immunity
title Immune responses to Epstein–Barr virus: molecular interactions in the virus evasion of CD8(+) T cell immunity
title_full Immune responses to Epstein–Barr virus: molecular interactions in the virus evasion of CD8(+) T cell immunity
title_fullStr Immune responses to Epstein–Barr virus: molecular interactions in the virus evasion of CD8(+) T cell immunity
title_full_unstemmed Immune responses to Epstein–Barr virus: molecular interactions in the virus evasion of CD8(+) T cell immunity
title_short Immune responses to Epstein–Barr virus: molecular interactions in the virus evasion of CD8(+) T cell immunity
title_sort immune responses to epstein–barr virus: molecular interactions in the virus evasion of cd8(+) t cell immunity
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2832755/
https://www.ncbi.nlm.nih.gov/pubmed/20004735
http://dx.doi.org/10.1016/j.micinf.2009.12.001
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AT zuojianmin immuneresponsestoepsteinbarrvirusmolecularinteractionsinthevirusevasionofcd8tcellimmunity

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