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Effects of a dual CCR3 and H(1)-antagonist on symptoms and eosinophilic inflammation in allergic rhinitis

BACKGROUND: The CC-chemokine receptor-3 (CCR3) has emerged as a target molecule for pharmacological intervention in allergic inflammation. OBJECTIVE: To examine whether a dual CCR3 and H(1)-receptor antagonist (AZD3778) affects allergic inflammation and symptoms in allergic rhinitis. METHODS: Patien...

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Detalles Bibliográficos
Autores principales: Greiff, Lennart, Ahlström-Emanuelsson, Cecilia, Bahl, Ash, Bengtsson, Thomas, Dahlström, Kerstin, Erjefält, Jonas, Widegren, Henrik, Andersson, Morgan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2833142/
https://www.ncbi.nlm.nih.gov/pubmed/20144207
http://dx.doi.org/10.1186/1465-9921-11-17

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