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A New Adenovirus Based Vaccine Vector Expressing an Eimeria tenella Derived TLR Agonist Improves Cellular Immune Responses to an Antigenic Target

BACKGROUND: Adenoviral based vectors remain promising vaccine platforms for use against numerous pathogens, including HIV. Recent vaccine trials utilizing Adenovirus based vaccines expressing HIV antigens confirmed induction of cellular immune responses, but these responses failed to prevent HIV inf...

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Detalles Bibliográficos
Autores principales: Appledorn, Daniel M., Aldhamen, Yasser A., DePas, William, Seregin, Sergey S., Liu, Chyong-Jy J., Schuldt, Nathan, Quach, Darin, Quiroga, Dionisia, Godbehere, Sarah, Zlatkin, Igor, Kim, Sungjin, McCormick, J. Justin, Amalfitano, Andrea
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2833191/
https://www.ncbi.nlm.nih.gov/pubmed/20221448
http://dx.doi.org/10.1371/journal.pone.0009579