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A Recombination Hotspot in a Schizophrenia-Associated Region of GABRB2
BACKGROUND: Schizophrenia is a major disorder with complex genetic mechanisms. Earlier, population genetic studies revealed the occurrence of strong positive selection in the GABRB2 gene encoding the β(2) subunit of GABA(A) receptors, within a segment of 3,551 bp harboring twenty-nine single nucleot...
Autores principales: | Ng, Siu-Kin, Lo, Wing-Sze, Pun, Frank W., Zhao, Cunyou, Yu, Zhiliang, Chen, Jianhuan, Tong, Ka-Lok, Xu, Zhiwen, Tsang, Shui-Ying, Yang, Qiang, Yu, Weichuan, Nimgaonkar, Vishwajit, Stöber, Gerald, Harano, Mutsuo, Xue, Hong |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2833194/ https://www.ncbi.nlm.nih.gov/pubmed/20221451 http://dx.doi.org/10.1371/journal.pone.0009547 |
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