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Phosphorylation of Human Tristetraprolin in Response to Its Interaction with the Cbl Interacting Protein CIN85
BACKGROUND: Tristetraprolin (TTP) is the prototype member of a family of CCCH tandem zinc finger proteins and is considered to be an anti-inflammatory protein in mammals. TTP plays a critical role in the decay of tumor necrosis factor alpha (TNF) mRNA, among others, by binding AU-rich RNA elements i...
Autores principales: | Kedar, Vishram P., Darby, Martyn K., Williams, Jason G., Blackshear, Perry J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2833206/ https://www.ncbi.nlm.nih.gov/pubmed/20221403 http://dx.doi.org/10.1371/journal.pone.0009588 |
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