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Hypoxia inducible factors in cancer stem cells

Oxygen is an essential regulator of cellular metabolism, survival, and proliferation. Cellular responses to oxygen levels are monitored, in part, by the transcriptional activity of the hypoxia inducible factors (HIFs). Under hypoxia, HIFs regulate a variety of pro-angiogenic and pro-glycolysis pathw...

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Detalles Bibliográficos
Autores principales: Heddleston, J M, Li, Z, Lathia, J D, Bao, S, Hjelmeland, A B, Rich, J N
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2833246/
https://www.ncbi.nlm.nih.gov/pubmed/20104230
http://dx.doi.org/10.1038/sj.bjc.6605551