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Hypoxia inducible factors in cancer stem cells
Oxygen is an essential regulator of cellular metabolism, survival, and proliferation. Cellular responses to oxygen levels are monitored, in part, by the transcriptional activity of the hypoxia inducible factors (HIFs). Under hypoxia, HIFs regulate a variety of pro-angiogenic and pro-glycolysis pathw...
Autores principales: | Heddleston, J M, Li, Z, Lathia, J D, Bao, S, Hjelmeland, A B, Rich, J N |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2833246/ https://www.ncbi.nlm.nih.gov/pubmed/20104230 http://dx.doi.org/10.1038/sj.bjc.6605551 |
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