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The role of zinc in the anti-tumour and anti-cachectic activity of D-myo-inositol 1,2,6-triphosphate

BACKGROUND: D-myo-inositol-1,2,6-triphosphate (α-trinositol, AT) is a polyanionic molecule capable of chelating divalent metal ions with anti-tumour and anti-cachectic activity in a murine model. METHODS: To investigate the role of zinc in this process, mice bearing cachexia-inducing MAC16 tumour we...

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Detalles Bibliográficos
Autores principales:	Russell, S T, Siren, P M A, Siren, M J, Tisdale, M J
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2010
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2833253/ https://www.ncbi.nlm.nih.gov/pubmed/20145616 http://dx.doi.org/10.1038/sj.bjc.6605562

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