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Well-Differentiated Extraskeletal Osteosarcoma Arising from the Retroperitoneum That Recurred as Anaplastic Spindle Cell Sarcoma

Extraskeletal osteosarcoma is an uncommon high-grade malignant soft tissue sarcoma. Well-differentiated extraskeletal osteosarcoma is thought to have a better prognosis than classical extraskeletal osteosarcoma, but dedifferentiation after recurrence has also been reported. We present a case of a pr...

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Autores principales: Arai, Hiromasa, Rino, Yasushi, Nishii, Teppei, Yukawa, Norio, Wada, Nobuyuki, Oshiro, Hisashi, Ishida, Tsuyoshi, Nakaigawa, Noboru, Masuda, Munetaka
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2833305/
https://www.ncbi.nlm.nih.gov/pubmed/20224645
http://dx.doi.org/10.1155/2010/327591
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author Arai, Hiromasa
Rino, Yasushi
Nishii, Teppei
Yukawa, Norio
Wada, Nobuyuki
Oshiro, Hisashi
Ishida, Tsuyoshi
Nakaigawa, Noboru
Masuda, Munetaka
author_facet Arai, Hiromasa
Rino, Yasushi
Nishii, Teppei
Yukawa, Norio
Wada, Nobuyuki
Oshiro, Hisashi
Ishida, Tsuyoshi
Nakaigawa, Noboru
Masuda, Munetaka
author_sort Arai, Hiromasa
collection PubMed
description Extraskeletal osteosarcoma is an uncommon high-grade malignant soft tissue sarcoma. Well-differentiated extraskeletal osteosarcoma is thought to have a better prognosis than classical extraskeletal osteosarcoma, but dedifferentiation after recurrence has also been reported. We present a case of a primary retroperitoneal extraskeletal osteosarcoma in a 62-year-old Japanese woman. Abdominal CT revealed a large mass with diffuse calcification in the right retroperitoneal space and tumor resection was performed. The histopathological diagnosis was well-differentiated retroperitoneal extraskeletal osteosarcoma. She was followed up by CT every 6 months without adjuvant radiotherapy and chemotherapy for 31 months until anaplastic high-grade spindle cell sarcoma recurred in the retroperitoneum. Our case is the seventh reported description of well-differentiated extraskeletal sarcoma, and the first to arise in the retroperitoneum and recur as an entirely dedifferentiated spindle cell sarcoma.
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spelling pubmed-28333052010-03-11 Well-Differentiated Extraskeletal Osteosarcoma Arising from the Retroperitoneum That Recurred as Anaplastic Spindle Cell Sarcoma Arai, Hiromasa Rino, Yasushi Nishii, Teppei Yukawa, Norio Wada, Nobuyuki Oshiro, Hisashi Ishida, Tsuyoshi Nakaigawa, Noboru Masuda, Munetaka Case Rep Med Case Report Extraskeletal osteosarcoma is an uncommon high-grade malignant soft tissue sarcoma. Well-differentiated extraskeletal osteosarcoma is thought to have a better prognosis than classical extraskeletal osteosarcoma, but dedifferentiation after recurrence has also been reported. We present a case of a primary retroperitoneal extraskeletal osteosarcoma in a 62-year-old Japanese woman. Abdominal CT revealed a large mass with diffuse calcification in the right retroperitoneal space and tumor resection was performed. The histopathological diagnosis was well-differentiated retroperitoneal extraskeletal osteosarcoma. She was followed up by CT every 6 months without adjuvant radiotherapy and chemotherapy for 31 months until anaplastic high-grade spindle cell sarcoma recurred in the retroperitoneum. Our case is the seventh reported description of well-differentiated extraskeletal sarcoma, and the first to arise in the retroperitoneum and recur as an entirely dedifferentiated spindle cell sarcoma. Hindawi Publishing Corporation 2010 2010-03-04 /pmc/articles/PMC2833305/ /pubmed/20224645 http://dx.doi.org/10.1155/2010/327591 Text en Copyright © 2010 Hiromasa Arai et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Arai, Hiromasa
Rino, Yasushi
Nishii, Teppei
Yukawa, Norio
Wada, Nobuyuki
Oshiro, Hisashi
Ishida, Tsuyoshi
Nakaigawa, Noboru
Masuda, Munetaka
Well-Differentiated Extraskeletal Osteosarcoma Arising from the Retroperitoneum That Recurred as Anaplastic Spindle Cell Sarcoma
title Well-Differentiated Extraskeletal Osteosarcoma Arising from the Retroperitoneum That Recurred as Anaplastic Spindle Cell Sarcoma
title_full Well-Differentiated Extraskeletal Osteosarcoma Arising from the Retroperitoneum That Recurred as Anaplastic Spindle Cell Sarcoma
title_fullStr Well-Differentiated Extraskeletal Osteosarcoma Arising from the Retroperitoneum That Recurred as Anaplastic Spindle Cell Sarcoma
title_full_unstemmed Well-Differentiated Extraskeletal Osteosarcoma Arising from the Retroperitoneum That Recurred as Anaplastic Spindle Cell Sarcoma
title_short Well-Differentiated Extraskeletal Osteosarcoma Arising from the Retroperitoneum That Recurred as Anaplastic Spindle Cell Sarcoma
title_sort well-differentiated extraskeletal osteosarcoma arising from the retroperitoneum that recurred as anaplastic spindle cell sarcoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2833305/
https://www.ncbi.nlm.nih.gov/pubmed/20224645
http://dx.doi.org/10.1155/2010/327591
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