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The Adenovirus Type 3 Dodecahedron's RGD Loop Comprises an HSPG Binding Site That Influences Integrin Binding

Human type 3 adenovirus dodecahedron (a virus like particle made of twelve penton bases) features the ability to enter cells through Heparan Sulphate Proteoglycans (HSPGs) and integrins interaction and is used as a versatile vector to deliver DNA or proteins. Cryo-EM reconstruction of the pseudovira...

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Detalles Bibliográficos
Autores principales:	Gout, E., Schoehn, G., Fenel, D., Lortat-Jacob, H., Fender, P.
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2833306/ https://www.ncbi.nlm.nih.gov/pubmed/20224646 http://dx.doi.org/10.1155/2010/541939

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