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Downregulation of Epidermal Growth Factor Receptor Expression Contributes to α-TEA's Proapoptotic Effects in Human Ovarian Cancer Cell Lines

RRR-α-tocopherol derivative α-TEA (RRR-α-tocopherol ether-linked acetic acid analog) has been shown to be a potent antitumor agent both in vivo and in vitro. In this study, we investigated the effects of α-TEA on the expression of epidermal growth factor receptor (EGFR) family members, ErbB1, 2 and...

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Detalles Bibliográficos
Autores principales: Shun, Ming-Chieh, Yu, Weiping, Park, Sook-Kyung, Sanders, Bob G., Kline, Kimberly
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2833311/
https://www.ncbi.nlm.nih.gov/pubmed/20224651
http://dx.doi.org/10.1155/2010/824571

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