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Improved weight attainment of extremely low-gestational-age infants with bronchopulmonary dysplasia
OBJECTIVE: To determine whether changes in neonatal practice and morbidity since 2000 have improved the growth attainment of infants with bronchopulmonary dysplasia (BPD). STUDY DESIGN: We compared the respective z-scores of the weight, length and head circumference of extremely low-gestational-age...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834327/ https://www.ncbi.nlm.nih.gov/pubmed/19798043 http://dx.doi.org/10.1038/jp.2009.142 |
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author | Madden, J Kobaly, K Minich, N M Schluchter, M Wilson-Costello, D Hack, M |
author_facet | Madden, J Kobaly, K Minich, N M Schluchter, M Wilson-Costello, D Hack, M |
author_sort | Madden, J |
collection | PubMed |
description | OBJECTIVE: To determine whether changes in neonatal practice and morbidity since 2000 have improved the growth attainment of infants with bronchopulmonary dysplasia (BPD). STUDY DESIGN: We compared the respective z-scores of the weight, length and head circumference of extremely low-gestational-age infants (aged <28 weeks) with BPD at birth, 40 weeks and 20 months corrected age (CA) during two time periods, namely period I, 1996–1999 (n=117) and period II, 2000–2003 (n=105), and examined the effects of significant changes in neonatal practice, morbidities and neurosensory outcome on 20-month growth outcomes. RESULT: During the most recent period (2000–2003), there was a significant increase in mean weight z-scores (−1.60 vs −1.22) and decrease in rates of subnormal weight (40 vs 21%), P<0.05 at 20 months CA but not in those of length or head circumference. Significant predictors of the 20-month weight z-score included time period (period I vs II), duration of ventilator dependence and 20-month neurosensory abnormality (all P<0.05). CONCLUSION: Despite an improvement in weight since 2000, poor growth attainment remains a major problem among infants with BPD. |
format | Text |
id | pubmed-2834327 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-28343272010-03-29 Improved weight attainment of extremely low-gestational-age infants with bronchopulmonary dysplasia Madden, J Kobaly, K Minich, N M Schluchter, M Wilson-Costello, D Hack, M J Perinatol Original Article OBJECTIVE: To determine whether changes in neonatal practice and morbidity since 2000 have improved the growth attainment of infants with bronchopulmonary dysplasia (BPD). STUDY DESIGN: We compared the respective z-scores of the weight, length and head circumference of extremely low-gestational-age infants (aged <28 weeks) with BPD at birth, 40 weeks and 20 months corrected age (CA) during two time periods, namely period I, 1996–1999 (n=117) and period II, 2000–2003 (n=105), and examined the effects of significant changes in neonatal practice, morbidities and neurosensory outcome on 20-month growth outcomes. RESULT: During the most recent period (2000–2003), there was a significant increase in mean weight z-scores (−1.60 vs −1.22) and decrease in rates of subnormal weight (40 vs 21%), P<0.05 at 20 months CA but not in those of length or head circumference. Significant predictors of the 20-month weight z-score included time period (period I vs II), duration of ventilator dependence and 20-month neurosensory abnormality (all P<0.05). CONCLUSION: Despite an improvement in weight since 2000, poor growth attainment remains a major problem among infants with BPD. Nature Publishing Group 2010-02 2009-10-01 /pmc/articles/PMC2834327/ /pubmed/19798043 http://dx.doi.org/10.1038/jp.2009.142 Text en Copyright © 2010 Nature Publishing Group http://creativecommons.org/licenses/by-nc-sa/3.0/ This work is licensed under the Creative Commons Attribution-NonCommercial-Share Alike 3.0 License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/ |
spellingShingle | Original Article Madden, J Kobaly, K Minich, N M Schluchter, M Wilson-Costello, D Hack, M Improved weight attainment of extremely low-gestational-age infants with bronchopulmonary dysplasia |
title | Improved weight attainment of extremely low-gestational-age infants with bronchopulmonary dysplasia |
title_full | Improved weight attainment of extremely low-gestational-age infants with bronchopulmonary dysplasia |
title_fullStr | Improved weight attainment of extremely low-gestational-age infants with bronchopulmonary dysplasia |
title_full_unstemmed | Improved weight attainment of extremely low-gestational-age infants with bronchopulmonary dysplasia |
title_short | Improved weight attainment of extremely low-gestational-age infants with bronchopulmonary dysplasia |
title_sort | improved weight attainment of extremely low-gestational-age infants with bronchopulmonary dysplasia |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834327/ https://www.ncbi.nlm.nih.gov/pubmed/19798043 http://dx.doi.org/10.1038/jp.2009.142 |
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