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Androgens induce oxidative stress and radiation resistance in prostate cancer cells though NADPH oxidase

Androgen deprivation therapy (ADT) facilitates the response of prostate cancer (PC) to radiation. Androgens have been shown to induce elevated basal levels of reactive oxygen species (ROS) in PC, leading to adaptation to radiation-induced cytotoxic oxidative stress. Here, we show that androgens incr...

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Detalles Bibliográficos
Autores principales: Lu, J P, Monardo, L, Bryskin, I, Hou, Z F, Trachtenberg, J, Wilson, B C, Pinthus, J H
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834342/
https://www.ncbi.nlm.nih.gov/pubmed/19546883
http://dx.doi.org/10.1038/pcan.2009.24