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Androgens induce oxidative stress and radiation resistance in prostate cancer cells though NADPH oxidase
Androgen deprivation therapy (ADT) facilitates the response of prostate cancer (PC) to radiation. Androgens have been shown to induce elevated basal levels of reactive oxygen species (ROS) in PC, leading to adaptation to radiation-induced cytotoxic oxidative stress. Here, we show that androgens incr...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834342/ https://www.ncbi.nlm.nih.gov/pubmed/19546883 http://dx.doi.org/10.1038/pcan.2009.24 |