Antenatal allopurinol for reduction of birth asphyxia induced brain damage (ALLO-Trial); a randomized double blind placebo controlled multicenter study

BACKGROUND: Hypoxic-ischaemic encephalopathy is associated with development of cerebral palsy and cognitive disability later in life and is therefore one of the fundamental problems in perinatal medicine. The xanthine-oxidase inhibitor allopurinol reduces the formation of free radicals, thereby limi...

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Detalles Bibliográficos
Autores principales: Kaandorp, Joepe J, Benders, Manon JNL, Rademaker, Carin MA, Torrance, Helen L, Oudijk, Martijn A, de Haan, Timo R, Bloemenkamp, Kitty WM, Rijken, Monique, van Pampus, Maria G, Bos, Arie F, Porath, Martina M, Oetomo, Sidarto Bambang, Willekes, Christine, Gavilanes, AW Danilo, Wouters, Maurice GAJ, van Elburg, Ruurd M, Huisjes, Anjoke JM, Bakker, Saskia CMJER, van Meir, Claudia A, von Lindern, Jeannette, Boon, Janine, de Boer, Inge P, Rijnders, Robbert JP, Jacobs, Corrie JWFM, Uiterwaal, Cuno SPM, Mol, Ben Willem J, Visser, Gerard HA, van Bel, Frank, Derks, Jan B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Study protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834613/
https://www.ncbi.nlm.nih.gov/pubmed/20167117
http://dx.doi.org/10.1186/1471-2393-10-8

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