Keratin 19 marks poor differentiation and a more aggressive behaviour in canine and human hepatocellular tumours

BACKGROUND: The expression of Keratin 19 (K19) was reported in a subset of hepatocellular carcinomas (HCCs). K19 positive HCCs are associated with an increased malignancy compared to K19 negative HCCs. No suitable mouse models exist for this subtype of HCC, nor is the incidence of K19 expression in...

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Detalles Bibliográficos
Autores principales: van Sprundel, Renee GHM, van den Ingh, Ted SGAM, Desmet, Valeer J, Katoonizadeh, Azeam, Penning, Louis C, Rothuizen, Jan, Roskams, Tania, Spee, Bart
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834617/
https://www.ncbi.nlm.nih.gov/pubmed/20167095
http://dx.doi.org/10.1186/1476-5926-9-4

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