Simultaneous CXCL12 and ESR1 CpG island hypermethylation correlates with poor prognosis in sporadic breast cancer

BACKGROUND: CXCL12 is a chemokine that is constitutively expressed in many organs and tissues. CXCL12 promoter hypermethylation has been detected in primary breast tumours and contributes to their metastatic potential. It has been shown that the oestrogen receptor α (ESR1) gene can also be silenced...

Descripción completa

Detalles Bibliográficos
Autores principales: Ramos, Edneia AS, Camargo, Anamaria A, Braun, Karin, Slowik, Renata, Cavalli, Iglenir J, Ribeiro, Enilze MSF, Pedrosa, Fábio de O, de Souza, Emanuel M, Costa, Fabrício F, Klassen, Giseli
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834618/
https://www.ncbi.nlm.nih.gov/pubmed/20109227
http://dx.doi.org/10.1186/1471-2407-10-23

Ejemplares similares

Ejemplares similares