Endothelial progenitor cells: what use for the cardiologist?

Endothelial Progenitor Cells (EPC) were first described in 1997 and have since been the subject of numerous investigative studies exploring the potential of these cells in the process of cardiovascular damage and repair. Whilst their exact definition and mechanism of action remains unclear, they are...

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Detalles Bibliográficos
Autores principales: Siddique, Aurangzeb, Shantsila, Eduard, Lip, Gregory YH, Varma, Chetan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834645/
https://www.ncbi.nlm.nih.gov/pubmed/20298532
http://dx.doi.org/10.1186/2040-2384-2-6
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author Siddique, Aurangzeb
Shantsila, Eduard
Lip, Gregory YH
Varma, Chetan
author_facet Siddique, Aurangzeb
Shantsila, Eduard
Lip, Gregory YH
Varma, Chetan
author_sort Siddique, Aurangzeb
collection PubMed
description Endothelial Progenitor Cells (EPC) were first described in 1997 and have since been the subject of numerous investigative studies exploring the potential of these cells in the process of cardiovascular damage and repair. Whilst their exact definition and mechanism of action remains unclear, they are directly influenced by different cardiovascular risk factors and have a definite role to play in defining cardiovascular risk. Furthermore, EPCs may have important therapeutic implications and further understanding of their pathophysiology has enabled us to explore new possibilities in the management of cardiovascular disease. This review article aims to provide an overview of the vast literature on EPCs in relation to clinical cardiology.
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spelling pubmed-28346452010-03-09 Endothelial progenitor cells: what use for the cardiologist? Siddique, Aurangzeb Shantsila, Eduard Lip, Gregory YH Varma, Chetan J Angiogenes Res Review Endothelial Progenitor Cells (EPC) were first described in 1997 and have since been the subject of numerous investigative studies exploring the potential of these cells in the process of cardiovascular damage and repair. Whilst their exact definition and mechanism of action remains unclear, they are directly influenced by different cardiovascular risk factors and have a definite role to play in defining cardiovascular risk. Furthermore, EPCs may have important therapeutic implications and further understanding of their pathophysiology has enabled us to explore new possibilities in the management of cardiovascular disease. This review article aims to provide an overview of the vast literature on EPCs in relation to clinical cardiology. BioMed Central 2010-02-22 /pmc/articles/PMC2834645/ /pubmed/20298532 http://dx.doi.org/10.1186/2040-2384-2-6 Text en Copyright ©2010 Siddique et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Siddique, Aurangzeb
Shantsila, Eduard
Lip, Gregory YH
Varma, Chetan
Endothelial progenitor cells: what use for the cardiologist?
title Endothelial progenitor cells: what use for the cardiologist?
title_full Endothelial progenitor cells: what use for the cardiologist?
title_fullStr Endothelial progenitor cells: what use for the cardiologist?
title_full_unstemmed Endothelial progenitor cells: what use for the cardiologist?
title_short Endothelial progenitor cells: what use for the cardiologist?
title_sort endothelial progenitor cells: what use for the cardiologist?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834645/
https://www.ncbi.nlm.nih.gov/pubmed/20298532
http://dx.doi.org/10.1186/2040-2384-2-6
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AT shantsilaeduard endothelialprogenitorcellswhatuseforthecardiologist
AT lipgregoryyh endothelialprogenitorcellswhatuseforthecardiologist
AT varmachetan endothelialprogenitorcellswhatuseforthecardiologist

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