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Mitotic slippage in non-cancer cells induced by a microtubule disruptor, disorazole C(1)

BACKGROUND: Disorazoles are polyene macrodiolides isolated from a myxobacterium fermentation broth. Disorazole C(1 )was newly synthesized and found to depolymerize microtubules and cause mitotic arrest. Here we examined the cellular responses to disorazole C(1 )in both non-cancer and cancer cells an...

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Detalles Bibliográficos
Autores principales:	Xu, Fengfeng L, Rbaibi, Youssef, Kiselyov, Kirill, Lazo, John S, Wipf, Peter, Saunders, William S
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834648/ https://www.ncbi.nlm.nih.gov/pubmed/20181182 http://dx.doi.org/10.1186/1472-6769-10-1

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