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Computational Study of Evolutionary Selection Pressure on Rainbow Trout Estrogen Receptors
Molecular dynamics simulations were used to determine the binding affinities between the hormone 17[Image: see text]-estradiol (E2) and different estrogen receptor (ER) isoforms in the rainbow trout, Oncorhynchus mykiss. Previous phylogenetic analysis indicates that a whole genome duplication prior...
Autores principales: | Shyu, Conrad, Brown, Celeste J., Ytreberg, F. Marty |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834741/ https://www.ncbi.nlm.nih.gov/pubmed/20231885 http://dx.doi.org/10.1371/journal.pone.0009392 |
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