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Atomic Analysis of Protein-Protein Interfaces with Known Inhibitors: The 2P2I Database

BACKGROUND: In the last decade, the inhibition of protein-protein interactions (PPIs) has emerged from both academic and private research as a new way to modulate the activity of proteins. Inhibitors of these original interactions are certainly the next generation of highly innovative drugs that wil...

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Detalles Bibliográficos
Autores principales: Bourgeas, Raphaël, Basse, Marie-Jeanne, Morelli, Xavier, Roche, Philippe
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834754/
https://www.ncbi.nlm.nih.gov/pubmed/20231898
http://dx.doi.org/10.1371/journal.pone.0009598