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Regulation of Proapoptotic Mammalian ste20–Like Kinase MST2 by the IGF1-Akt Pathway

BACKGROUND: Hippo, a Drosophila serine/threonine kinase, promotes apoptosis and restricts cell growth and proliferation. Its mammalian homolog MST2 has been shown to play similar role and be regulated by Raf-1 via a kinase-independent mechanism and by RASSF family proteins through forming complex wi...

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Detalles Bibliográficos
Autores principales:	Kim, Donghwa, Shu, Shaokun, Coppola, Marc D., Kaneko, Satoshi, Yuan, Zeng-qiang, Cheng, Jin Q.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834758/ https://www.ncbi.nlm.nih.gov/pubmed/20231902 http://dx.doi.org/10.1371/journal.pone.0009616

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