Cargando…
Feedback between p21 and reactive oxygen production is necessary for cell senescence
Cellular senescence—the permanent arrest of cycling in normally proliferating cells such as fibroblasts—contributes both to age-related loss of mammalian tissue homeostasis and acts as a tumour suppressor mechanism. The pathways leading to establishment of senescence are proving to be more complex t...
| Autores principales: | , , , , , , , , , , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
European Molecular Biology Organization
2010
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835567/ https://www.ncbi.nlm.nih.gov/pubmed/20160708 http://dx.doi.org/10.1038/msb.2010.5 |