Neoadjuvant multidrug chemotherapy including High-Dose Methotrexate modifies VEGF expression in Osteosarcoma: an immunohistochemical analysis

BACKGROUND: Angiogenesis plays a role in the progression of osteosarcoma, as well as in other mesenchymal tumors and carcinomas, and it is most commonly assessed by vascular endothelial growth factor (VEGF) expression or tumor CD31-positive microvessel density (MVD). Tumor VEGF expression is predict...

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Detalles Bibliográficos
Autores principales: Rossi, Barbara, Schinzari, Giovanni, Maccauro, Giulio, Scaramuzzo, Laura, Signorelli, Diego, Rosa, Michele A, Fabbriciani, Carlo, Carlo, Barone
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835659/
https://www.ncbi.nlm.nih.gov/pubmed/20158913
http://dx.doi.org/10.1186/1471-2474-11-34

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