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Sirtuin1-p53, forkhead box O3a, p38 and post-infarct cardiac remodeling in the spontaneously diabetic Goto-Kakizaki rat
BACKGROUND: Diabetes is associated with changes in myocardial stress-response pathways and is recognized as an independent risk factor for cardiac remodeling. Using spontaneously diabetic Goto Kakizaki rats as a model of type 2 DM we investigated whether post-translational modifications in the Akt -...
Autores principales: | Vahtola, Erik, Louhelainen, Marjut, Forstén, Hanna, Merasto, Saara, Raivio, Johanna, Kaheinen, Petri, Kytö, Ville, Tikkanen, Ilkka, Levijoki, Jouko, Mervaala, Eero |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835668/ https://www.ncbi.nlm.nih.gov/pubmed/20105289 http://dx.doi.org/10.1186/1475-2840-9-5 |
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