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Distinct and redundant functions of cyclin E1 and cyclin E2 in development and cancer
The highly conserved E-type cyclins are core components of the cell cycle machinery, facilitating the transition into S phase through activation of the cyclin dependent kinases, and assembly of pre-replication complexes on DNA. Cyclin E1 and cyclin E2 are assumed to be functionally redundant, as cyc...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835679/ https://www.ncbi.nlm.nih.gov/pubmed/20180967 http://dx.doi.org/10.1186/1747-1028-5-2 |