Disruption of Astrocyte STAT3 Signaling Decreases Mitochondrial Function and Increases Oxidative Stress In Vitro

BACKGROUND: Astrocytes exert a wide variety of functions in health and disease and respond to a wide range of signaling pathways, including members of the Janus-kinase signal transducers and activators of transcription (Jak-STAT) family. We have recently shown that STAT3 is an important regulator of...

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Detalles Bibliográficos
Autores principales: Sarafian, Theodore A., Montes, Cindy, Imura, Tetsuya, Qi, Jingwei, Coppola, Giovanni, Geschwind, Daniel H., Sofroniew, Michael V.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835741/
https://www.ncbi.nlm.nih.gov/pubmed/20224768
http://dx.doi.org/10.1371/journal.pone.0009532

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