Reactivation of Latent Tuberculosis in Cynomolgus Macaques Infected with SIV Is Associated with Early Peripheral T Cell Depletion and Not Virus Load

HIV-infected individuals with latent Mycobacterium tuberculosis (Mtb) infection are at significantly greater risk of reactivation tuberculosis (TB) than HIV-negative individuals with latent TB, even while CD4 T cell numbers are well preserved. Factors underlying high rates of reactivation are poorly...

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Detalles Bibliográficos
Autores principales: Diedrich, Collin R., Mattila, Joshua T., Klein, Edwin, Janssen, Chris, Phuah, Jiayao, Sturgeon, Timothy J., Montelaro, Ronald C., Lin, Philana Ling, Flynn, JoAnne L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835744/
https://www.ncbi.nlm.nih.gov/pubmed/20224771
http://dx.doi.org/10.1371/journal.pone.0009611

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