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The SUMO protease SENP6 is essential for inner kinetochore assembly

We have analyzed the mitotic function of SENP6, a small ubiquitin-like modifier (SUMO) protease that disassembles conjugated SUMO-2/3 chains. Cells lacking SENP6 showed defects in spindle assembly and metaphase chromosome congression. Analysis of kinetochore composition in these cells revealed that...

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Detalles Bibliográficos
Autores principales:	Mukhopadhyay, Debaditya, Arnaoutov, Alexei, Dasso, Mary
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2010
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835930/ https://www.ncbi.nlm.nih.gov/pubmed/20212317 http://dx.doi.org/10.1083/jcb.200909008

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