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Solution structure of the Drosha double-stranded RNA-binding domain
BACKGROUND: Drosha is a nuclear RNase III enzyme that initiates processing of regulatory microRNA. Together with partner protein DiGeorge syndrome critical region 8 (DGCR8), it forms the Microprocessor complex, which cleaves precursor transcripts called primary microRNA to produce hairpin precursor...
Autores principales: | Mueller, Geoffrey A, Miller, Matthew T, DeRose, Eugene F, Ghosh, Mahua, London, Robert E, Hall, Traci M Tanaka |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836000/ https://www.ncbi.nlm.nih.gov/pubmed/20226070 http://dx.doi.org/10.1186/1758-907X-1-2 |
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