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Rapidly Evolving Giant Dermatofibroma
Dermatofibroma, also known as “fibrous histiocytoma”, is a benign dermal or subcutaneous poorly circumscribed proliferation of spindle-shaped fibroblasts and macrophages in the dermis. Although it is commonly present as a brownish nodule the legs of females, it may also arise on the upper extremitie...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
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Hindawi Publishing Corporation
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836174/ https://www.ncbi.nlm.nih.gov/pubmed/20224764 http://dx.doi.org/10.1155/2010/620910 |
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author | Lang, K. J. Lidder, S. Hofer, M. Graham, C. Taylor, A. |
author_facet | Lang, K. J. Lidder, S. Hofer, M. Graham, C. Taylor, A. |
author_sort | Lang, K. J. |
collection | PubMed |
description | Dermatofibroma, also known as “fibrous histiocytoma”, is a benign dermal or subcutaneous poorly circumscribed proliferation of spindle-shaped fibroblasts and macrophages in the dermis. Although it is commonly present as a brownish nodule the legs of females, it may also arise on the upper extremities, trunk, and rarely on the head. The exact pathogenesis is unclear. However, it is widely believed that the originating insult to the dermis is a folliculitis, an arthropod bite, or an unspecified initial inflammatory condition. Giant dermatofibromas of greater than 5 cm in diameter are rare, with only 22 cases reported in the literature. We present a case of a rapidly evolving pedunculated mass in the groin of a male patient. Histological examination confirmed this to be a giant dermatofibroma. Though this specimen cannot is not confirmed as such, the cellular subtype is sometimes present as a larger lesion with anecdotal reports of local recurrence and distant metastases. The clinical and radiological features which were somewhat suspicious of malignancy are considered in the context of the definitive pathological diagnosis of a benign lesion. |
format | Text |
id | pubmed-2836174 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-28361742010-03-11 Rapidly Evolving Giant Dermatofibroma Lang, K. J. Lidder, S. Hofer, M. Graham, C. Taylor, A. Case Rep Med Case Report Dermatofibroma, also known as “fibrous histiocytoma”, is a benign dermal or subcutaneous poorly circumscribed proliferation of spindle-shaped fibroblasts and macrophages in the dermis. Although it is commonly present as a brownish nodule the legs of females, it may also arise on the upper extremities, trunk, and rarely on the head. The exact pathogenesis is unclear. However, it is widely believed that the originating insult to the dermis is a folliculitis, an arthropod bite, or an unspecified initial inflammatory condition. Giant dermatofibromas of greater than 5 cm in diameter are rare, with only 22 cases reported in the literature. We present a case of a rapidly evolving pedunculated mass in the groin of a male patient. Histological examination confirmed this to be a giant dermatofibroma. Though this specimen cannot is not confirmed as such, the cellular subtype is sometimes present as a larger lesion with anecdotal reports of local recurrence and distant metastases. The clinical and radiological features which were somewhat suspicious of malignancy are considered in the context of the definitive pathological diagnosis of a benign lesion. Hindawi Publishing Corporation 2010 2010-03-09 /pmc/articles/PMC2836174/ /pubmed/20224764 http://dx.doi.org/10.1155/2010/620910 Text en https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Lang, K. J. Lidder, S. Hofer, M. Graham, C. Taylor, A. Rapidly Evolving Giant Dermatofibroma |
title | Rapidly Evolving Giant Dermatofibroma |
title_full | Rapidly Evolving Giant Dermatofibroma |
title_fullStr | Rapidly Evolving Giant Dermatofibroma |
title_full_unstemmed | Rapidly Evolving Giant Dermatofibroma |
title_short | Rapidly Evolving Giant Dermatofibroma |
title_sort | rapidly evolving giant dermatofibroma |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836174/ https://www.ncbi.nlm.nih.gov/pubmed/20224764 http://dx.doi.org/10.1155/2010/620910 |
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