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Rapidly Evolving Giant Dermatofibroma

Dermatofibroma, also known as “fibrous histiocytoma”, is a benign dermal or subcutaneous poorly circumscribed proliferation of spindle-shaped fibroblasts and macrophages in the dermis. Although it is commonly present as a brownish nodule the legs of females, it may also arise on the upper extremitie...

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Autores principales: Lang, K. J., Lidder, S., Hofer, M., Graham, C., Taylor, A.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836174/
https://www.ncbi.nlm.nih.gov/pubmed/20224764
http://dx.doi.org/10.1155/2010/620910
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author Lang, K. J.
Lidder, S.
Hofer, M.
Graham, C.
Taylor, A.
author_facet Lang, K. J.
Lidder, S.
Hofer, M.
Graham, C.
Taylor, A.
author_sort Lang, K. J.
collection PubMed
description Dermatofibroma, also known as “fibrous histiocytoma”, is a benign dermal or subcutaneous poorly circumscribed proliferation of spindle-shaped fibroblasts and macrophages in the dermis. Although it is commonly present as a brownish nodule the legs of females, it may also arise on the upper extremities, trunk, and rarely on the head. The exact pathogenesis is unclear. However, it is widely believed that the originating insult to the dermis is a folliculitis, an arthropod bite, or an unspecified initial inflammatory condition. Giant dermatofibromas of greater than 5 cm in diameter are rare, with only 22 cases reported in the literature. We present a case of a rapidly evolving pedunculated mass in the groin of a male patient. Histological examination confirmed this to be a giant dermatofibroma. Though this specimen cannot is not confirmed as such, the cellular subtype is sometimes present as a larger lesion with anecdotal reports of local recurrence and distant metastases. The clinical and radiological features which were somewhat suspicious of malignancy are considered in the context of the definitive pathological diagnosis of a benign lesion.
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spelling pubmed-28361742010-03-11 Rapidly Evolving Giant Dermatofibroma Lang, K. J. Lidder, S. Hofer, M. Graham, C. Taylor, A. Case Rep Med Case Report Dermatofibroma, also known as “fibrous histiocytoma”, is a benign dermal or subcutaneous poorly circumscribed proliferation of spindle-shaped fibroblasts and macrophages in the dermis. Although it is commonly present as a brownish nodule the legs of females, it may also arise on the upper extremities, trunk, and rarely on the head. The exact pathogenesis is unclear. However, it is widely believed that the originating insult to the dermis is a folliculitis, an arthropod bite, or an unspecified initial inflammatory condition. Giant dermatofibromas of greater than 5 cm in diameter are rare, with only 22 cases reported in the literature. We present a case of a rapidly evolving pedunculated mass in the groin of a male patient. Histological examination confirmed this to be a giant dermatofibroma. Though this specimen cannot is not confirmed as such, the cellular subtype is sometimes present as a larger lesion with anecdotal reports of local recurrence and distant metastases. The clinical and radiological features which were somewhat suspicious of malignancy are considered in the context of the definitive pathological diagnosis of a benign lesion. Hindawi Publishing Corporation 2010 2010-03-09 /pmc/articles/PMC2836174/ /pubmed/20224764 http://dx.doi.org/10.1155/2010/620910 Text en https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Lang, K. J.
Lidder, S.
Hofer, M.
Graham, C.
Taylor, A.
Rapidly Evolving Giant Dermatofibroma
title Rapidly Evolving Giant Dermatofibroma
title_full Rapidly Evolving Giant Dermatofibroma
title_fullStr Rapidly Evolving Giant Dermatofibroma
title_full_unstemmed Rapidly Evolving Giant Dermatofibroma
title_short Rapidly Evolving Giant Dermatofibroma
title_sort rapidly evolving giant dermatofibroma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836174/
https://www.ncbi.nlm.nih.gov/pubmed/20224764
http://dx.doi.org/10.1155/2010/620910
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