Enrichment of homologs in insignificant BLAST hits by co-complex network alignment

BACKGROUND: Homology is a crucial concept in comparative genomics. The algorithm probably most widely used for homology detection in comparative genomics, is BLAST. Usually a stringent score cutoff is applied to distinguish putative homologs from possible false positive hits. As a consequence, some...

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Detalles Bibliográficos
Autores principales: Fokkens, Like, Botelho, Sandra MC, Boekhorst, Jos, Snel, Berend
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836305/
https://www.ncbi.nlm.nih.gov/pubmed/20152020
http://dx.doi.org/10.1186/1471-2105-11-86

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836305/
https://www.ncbi.nlm.nih.gov/pubmed/20152020
http://dx.doi.org/10.1186/1471-2105-11-86

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