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Enrichment of homologs in insignificant BLAST hits by co-complex network alignment
BACKGROUND: Homology is a crucial concept in comparative genomics. The algorithm probably most widely used for homology detection in comparative genomics, is BLAST. Usually a stringent score cutoff is applied to distinguish putative homologs from possible false positive hits. As a consequence, some...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836305/ https://www.ncbi.nlm.nih.gov/pubmed/20152020 http://dx.doi.org/10.1186/1471-2105-11-86 |