Acute NMDA toxicity in cultured rat cerebellar granule neurons is accompanied by autophagy induction and late onset autophagic cell death phenotype

BACKGROUND: Autophagy, an intracellular response to stress, is characterized by double membrane cytosolic vesicles called autophagosomes. Prolonged autophagy is known to result in autophagic (Type II) cell death. This study examined the potential role of an autophagic response in cultured cerebellar...

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Detalles Bibliográficos
Autores principales: Sadasivan, Shankar, Zhang, Zhiqun, Larner, Stephen F, Liu, Ming C, Zheng, Wenrong, Kobeissy, Firas H, Hayes, Ronald L, Wang, Kevin KW
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836363/
https://www.ncbi.nlm.nih.gov/pubmed/20167092
http://dx.doi.org/10.1186/1471-2202-11-21

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