Hepatobiliary neuroendocrine carcinoma: a case report

INTRODUCTION: Neuroendocrine carcinoma of the gallbladder is a rather uncommon disease. We report a case of a neuroendocrine tumor that was located in the wall of the gallbladder and that extended into the liver. CASE PRESENTATION: A 52-year-old Caucasian woman presented with right-sided abdominal p...

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Detalles Bibliográficos
Autores principales: Manxhuka-Kerliu, Suzana, Petrusevska, Gordana, Maloku, Halit, Sahatciu-Meka, Vjollca, Loxha, Sadushe, Loxha, Naim, Shahini, Labinot
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Case report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836365/
https://www.ncbi.nlm.nih.gov/pubmed/20370888
http://dx.doi.org/10.1186/1752-1947-4-53
Descripción
Sumario:INTRODUCTION: Neuroendocrine carcinoma of the gallbladder is a rather uncommon disease. We report a case of a neuroendocrine tumor that was located in the wall of the gallbladder and that extended into the liver. CASE PRESENTATION: A 52-year-old Caucasian woman presented with right-sided abdominal pain, ascites and jaundice. An MRI scan revealed a tumor mass located in the gallbladder wall and involving the liver. A partial hepatectomy and cholecystectomy were performed. Histology revealed a neuroendocrine tumor, which showed scattered Grimelius positive cells and immuno-expressed epithelial and endocrine markers. Our patient is undergoing chemotherapy treatment. CONCLUSION: Gastroenteropancreatic neuroendocrine tumors need a multidisciplinary approach, involving immunohistochemistry and molecular-genetic techniques.

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