Cargando…

BOLD Signal in Both Ipsilateral and Contralateral Retinotopic Cortex Modulates with Perceptual Fading

Under conditions of visual fixation, perceptual fading occurs when a stationary object, though present in the world and continually casting light upon the retina, vanishes from visual consciousness. The neural correlates of the consciousness of such an object will presumably modulate in activity wit...

Descripción completa

Detalles Bibliográficos
Autores principales: Hsieh, Po-Jang, Tse, Peter U.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836375/
https://www.ncbi.nlm.nih.gov/pubmed/20300177
http://dx.doi.org/10.1371/journal.pone.0009638
_version_ 1782178713659506688
author Hsieh, Po-Jang
Tse, Peter U.
author_facet Hsieh, Po-Jang
Tse, Peter U.
author_sort Hsieh, Po-Jang
collection PubMed
description Under conditions of visual fixation, perceptual fading occurs when a stationary object, though present in the world and continually casting light upon the retina, vanishes from visual consciousness. The neural correlates of the consciousness of such an object will presumably modulate in activity with the onset and cessation of perceptual fading. METHOD: In order to localize the neural correlates of perceptual fading, a green disk that had been individually set to be equiluminant with the orange background, was presented in one of the four visual quadrants; Subjects indicated with a button press whether or not the disk was subjectively visible as it perceptually faded in and out. RESULTS: Blood oxygen-level dependent (BOLD) signal in V1 and ventral retinotopic areas V2v and V3v decreases when the disk subjectively disappears, and increases when it subjectively reappears. This effect occurs in early visual areas both ipsilaterally and contralaterally to the fading figure. That is, it occurs regardless of whether the fading stimulus is presented inside or outside of the corresponding portion of visual field. In addition, we find that the microsaccade rate rises before and after perceptual transitions from not seeing to seeing the disk, and decreases before perceptual transitions from seeing to not seeing the disk. These BOLD signal changes could be driven by a global process that operates across contralateral and ipsilateral visual cortex or by a confounding factor, such as microsaccade rate.
format Text
id pubmed-2836375
institution National Center for Biotechnology Information
language English
publishDate 2010
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-28363752010-03-19 BOLD Signal in Both Ipsilateral and Contralateral Retinotopic Cortex Modulates with Perceptual Fading Hsieh, Po-Jang Tse, Peter U. PLoS One Research Article Under conditions of visual fixation, perceptual fading occurs when a stationary object, though present in the world and continually casting light upon the retina, vanishes from visual consciousness. The neural correlates of the consciousness of such an object will presumably modulate in activity with the onset and cessation of perceptual fading. METHOD: In order to localize the neural correlates of perceptual fading, a green disk that had been individually set to be equiluminant with the orange background, was presented in one of the four visual quadrants; Subjects indicated with a button press whether or not the disk was subjectively visible as it perceptually faded in and out. RESULTS: Blood oxygen-level dependent (BOLD) signal in V1 and ventral retinotopic areas V2v and V3v decreases when the disk subjectively disappears, and increases when it subjectively reappears. This effect occurs in early visual areas both ipsilaterally and contralaterally to the fading figure. That is, it occurs regardless of whether the fading stimulus is presented inside or outside of the corresponding portion of visual field. In addition, we find that the microsaccade rate rises before and after perceptual transitions from not seeing to seeing the disk, and decreases before perceptual transitions from seeing to not seeing the disk. These BOLD signal changes could be driven by a global process that operates across contralateral and ipsilateral visual cortex or by a confounding factor, such as microsaccade rate. Public Library of Science 2010-03-11 /pmc/articles/PMC2836375/ /pubmed/20300177 http://dx.doi.org/10.1371/journal.pone.0009638 Text en Hsieh, Tse. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Hsieh, Po-Jang
Tse, Peter U.
BOLD Signal in Both Ipsilateral and Contralateral Retinotopic Cortex Modulates with Perceptual Fading
title BOLD Signal in Both Ipsilateral and Contralateral Retinotopic Cortex Modulates with Perceptual Fading
title_full BOLD Signal in Both Ipsilateral and Contralateral Retinotopic Cortex Modulates with Perceptual Fading
title_fullStr BOLD Signal in Both Ipsilateral and Contralateral Retinotopic Cortex Modulates with Perceptual Fading
title_full_unstemmed BOLD Signal in Both Ipsilateral and Contralateral Retinotopic Cortex Modulates with Perceptual Fading
title_short BOLD Signal in Both Ipsilateral and Contralateral Retinotopic Cortex Modulates with Perceptual Fading
title_sort bold signal in both ipsilateral and contralateral retinotopic cortex modulates with perceptual fading
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836375/
https://www.ncbi.nlm.nih.gov/pubmed/20300177
http://dx.doi.org/10.1371/journal.pone.0009638
work_keys_str_mv AT hsiehpojang boldsignalinbothipsilateralandcontralateralretinotopiccortexmodulateswithperceptualfading
AT tsepeteru boldsignalinbothipsilateralandcontralateralretinotopiccortexmodulateswithperceptualfading