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Computing folding pathways between RNA secondary structures
Given an RNA sequence and two designated secondary structures A, B, we describe a new algorithm that computes a nearly optimal folding pathway from A to B. The algorithm, RNAtabupath, employs a tabu semi-greedy heuristic, known to be an effective search strategy in combinatorial optimization. Foldin...
Autores principales: | Dotu, Ivan, Lorenz, William A., Van Hentenryck, Pascal, Clote, Peter |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836545/ https://www.ncbi.nlm.nih.gov/pubmed/20044352 http://dx.doi.org/10.1093/nar/gkp1054 |
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