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PCNA and XPF cooperate to distort DNA substrates
XPF is a structure-specific endonuclease that preferentially cleaves 3′ DNA flaps during a variety of repair processes. The crystal structure of a crenarchaeal XPF protein bound to a DNA duplex yielded insights into how XPF might recognise branched DNA structures, and recent kinetic data have demons...
Autores principales: | Hutton, Richard D., Craggs, Timothy D., White, Malcolm F., Penedo, J.Carlos |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836553/ https://www.ncbi.nlm.nih.gov/pubmed/20008103 http://dx.doi.org/10.1093/nar/gkp1104 |
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