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Beyond Affymetrix arrays: expanding the set of known hybridization isotherms and observing pre-wash signal intensities
Microarray hybridization studies have attributed the nonlinearity of hybridization isotherms to probe saturation and post-hybridization washing. Both processes are thought to distort ‘true’ target abundance because immobilized probes are saturated with excess target and stringent washing removes loo...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836560/ https://www.ncbi.nlm.nih.gov/pubmed/19969547 http://dx.doi.org/10.1093/nar/gkp1122 |