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Toxin–antitoxin based transgene expression in mammalian cells
Long-term, recombinant gene expression in mammalian cells depends on the nature of the transgene integration site and its inherent properties to modulate transcription (epigenetic effects). Here we describe a method by which high transgene expression is achieved and stabilized in extensively prolife...
Autores principales: | Nehlsen, K., Herrmann, S., Zauers, J., Hauser, H., Wirth, D. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836568/ https://www.ncbi.nlm.nih.gov/pubmed/20007149 http://dx.doi.org/10.1093/nar/gkp1140 |
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