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Membrane association of mitochondrial DNA facilitates base excision repair in mammalian mitochondria

Mitochondrial DNA encodes a set of 13 polypeptides and is subjected to constant oxidative stress due to ROS production within the organelle. It has been shown that DNA repair in the mitochondrion proceeds through both short- and long-patch base excision repair (BER). In the present article, we have...

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Detalles Bibliográficos
Autores principales:	Boesch, Pierre, Ibrahim, Noha, Dietrich, André, Lightowlers, Robert N.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2010
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836570/ https://www.ncbi.nlm.nih.gov/pubmed/20007607 http://dx.doi.org/10.1093/nar/gkp1143

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