Cargando…

Membrane association of mitochondrial DNA facilitates base excision repair in mammalian mitochondria

Mitochondrial DNA encodes a set of 13 polypeptides and is subjected to constant oxidative stress due to ROS production within the organelle. It has been shown that DNA repair in the mitochondrion proceeds through both short- and long-patch base excision repair (BER). In the present article, we have...

Descripción completa

Detalles Bibliográficos
Autores principales:	Boesch, Pierre, Ibrahim, Noha, Dietrich, André, Lightowlers, Robert N.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2010
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836570/ https://www.ncbi.nlm.nih.gov/pubmed/20007607 http://dx.doi.org/10.1093/nar/gkp1143

Ejemplares similares

Plant mitochondria possess a short-patch base excision DNA repair pathway
por: Boesch, Pierre, et al.
Publicado: (2009)

Complementation of aprataxin deficiency by base excision repair enzymes in mitochondrial extracts
por: Çağlayan, Melike, et al.
Publicado: (2017)

Base and nucleotide excision repair facilitate resolution of platinum drugs-induced transcription blockage
por: Slyskova, Jana, et al.
Publicado: (2018)

Regulation of base excision repair: Ntg1 nuclear and mitochondrial dynamic localization in response to genotoxic stress
por: Swartzlander, Dan B., et al.
Publicado: (2010)

p38 MAPK- and Akt-mediated p300 phosphorylation regulates its degradation to facilitate nucleotide excision repair
por: Wang, Qi-En, et al.
Publicado: (2013)

Kinetics of endogenous mouse FEN1 in base excision repair
por: Kleppa, Liv, et al.
Publicado: (2012)

Nucleotide excision repair of abasic DNA lesions
por: Kitsera, Nataliya, et al.
Publicado: (2019)

An interplay of the base excision repair and mismatch repair pathways in active DNA demethylation
por: Grin, Inga, et al.
Publicado: (2016)

Base excision repair of 8-oxoG in dinucleosomes
por: Menoni, Hervé, et al.
Publicado: (2012)

Mismatch repair and nucleotide excision repair proteins cooperate in the recognition of DNA interstrand crosslinks
por: Zhao, Junhua, et al.
Publicado: (2009)

Epistatic role of base excision repair and mismatch repair pathways in mediating cisplatin cytotoxicity
por: Kothandapani, Anbarasi, et al.
Publicado: (2013)

Modulation of base excision repair of 8-oxoguanine by the nucleotide sequence
por: Allgayer, Julia, et al.
Publicado: (2013)

Replication factors transiently associate with mtDNA at the mitochondrial inner membrane to facilitate replication
por: Rajala, Nina, et al.
Publicado: (2014)

A ubiquitylation site in Cockayne syndrome B required for repair of oxidative DNA damage, but not for transcription-coupled nucleotide excision repair
por: Ranes, Michael, et al.
Publicado: (2016)

p53 coordinates base excision repair to prevent genomic instability
por: Poletto, Mattia, et al.
Publicado: (2016)

Mechanism of lesion verification by the human XPD helicase in nucleotide excision repair
por: Fu, Iwen, et al.
Publicado: (2022)

Hydrolytic function of Exo1 in mammalian mismatch repair
por: Shao, Hongbing, et al.
Publicado: (2014)

A novel role for transcription-coupled nucleotide excision repair for the in vivo repair of 3,N(4)-ethenocytosine
por: Chaim, Isaac A., et al.
Publicado: (2017)

SIRT1 deacetylates APE1 and regulates cellular base excision repair
por: Yamamori, Tohru, et al.
Publicado: (2010)

Quantitative characterization of protein–protein complexes involved in base excision DNA repair
por: Moor, Nina A., et al.
Publicado: (2015)

Nucleotide excision repair efficiency in quiescent human fibroblasts is modulated by circadian clock
por: Bee, Leonardo, et al.
Publicado: (2015)

DICER and ZRF1 contribute to chromatin decondensation during nucleotide excision repair
por: Chitale, Shalaka, et al.
Publicado: (2017)

HECTD1 promotes base excision repair in nucleosomes through chromatin remodelling
por: Bennett, Laura, et al.
Publicado: (2020)

Repair of gaps opposite lesions by homologous recombination in mammalian cells
por: Adar, Sheera, et al.
Publicado: (2009)

Regulation of nucleotide excision repair activity by transcriptional and post-transcriptional control of the XPA protein
por: Kang, Tae-Hong, et al.
Publicado: (2011)

Chronic low-dose ultraviolet-induced mutagenesis in nucleotide excision repair-deficient cells
por: Haruta, Nami, et al.
Publicado: (2012)

AKAP12 mediates PKA-induced phosphorylation of ATR to enhance nucleotide excision repair
por: Jarrett, Stuart G., et al.
Publicado: (2016)

Transcription-coupled nucleotide excision repair is coordinated by ubiquitin and SUMO in response to ultraviolet irradiation
por: Liebelt, Frauke, et al.
Publicado: (2020)

Nucleotide excision repair in Human cell lines lacking both XPC and CSB proteins
por: Lindsey-Boltz, Laura A, et al.
Publicado: (2023)

The mechanism of the glycosylase reaction with hOGG1 base-excision repair enzyme: concerted effect of Lys249 and Asp268 during excision of 8-oxoguanine
por: Šebera, Jakub, et al.
Publicado: (2017)

XPD localizes in mitochondria and protects the mitochondrial genome from oxidative DNA damage
por: Liu, Jing, et al.
Publicado: (2015)

Oxidative stress triggers the preferential assembly of base excision repair complexes on open chromatin regions
por: Amouroux, Rachel, et al.
Publicado: (2010)

CBP and p300 acetylate PCNA to link its degradation with nucleotide excision repair synthesis
por: Cazzalini, Ornella, et al.
Publicado: (2014)

The PARP inhibitor Olaparib disrupts base excision repair of 5-aza-2′-deoxycytidine lesions
por: Orta, Manuel Luis, et al.
Publicado: (2014)

Active transcriptomic and proteomic reprogramming in the C. elegans nucleotide excision repair mutant xpa-1
por: Arczewska, Katarzyna D., et al.
Publicado: (2013)

Regulation of NEIL1 protein abundance by RAD9 is important for efficient base excision repair
por: Panigrahi, Sunil K., et al.
Publicado: (2015)

The Shu complex promotes error-free tolerance of alkylation-induced base excision repair products
por: Godin, Stephen K., et al.
Publicado: (2016)

Histones participate in base excision repair of 8-oxodGuo by transiently cross-linking with active repair intermediates in nucleosome core particles
por: Ren, Mengtian, et al.
Publicado: (2020)

Polymerases ε and ∂ repair dysfunctional telomeres facilitated by salt
por: Ivanova, Iglika G., et al.
Publicado: (2016)

UNG-initiated base excision repair is the major repair route for 5-fluorouracil in DNA, but 5-fluorouracil cytotoxicity depends mainly on RNA incorporation
por: Pettersen, Henrik Sahlin, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_idh7qu14ojv3frhq6kilgjugc0