Combinational Soluble N-Ethylmaleimide-sensitive Factor Attachment Protein Receptor Proteins VAMP8 and Vti1b Mediate Fusion of Antimicrobial and Canonical Autophagosomes with Lysosomes

Autophagy plays a crucial role in host defense, termed antimicrobial autophagy (xenophagy), as it functions to degrade intracellular foreign microbial invaders such as group A Streptococcus (GAS). Xenophagosomes undergo a stepwise maturation process consisting of a fusion event with lysosomes, after...

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Detalles Bibliográficos
Autores principales: Furuta, Nobumichi, Fujita, Naonobu, Noda, Takeshi, Yoshimori, Tamotsu, Amano, Atsuo
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836953/
https://www.ncbi.nlm.nih.gov/pubmed/20089838
http://dx.doi.org/10.1091/mbc.E09-08-0693

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