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Ras and Calcium Signaling Pathways Converge at Raf1 via the Shoc2 Scaffold Protein
Situated downstream of Ras is a key signaling molecule, Raf1. Increase in Ca(2+) concentration has been shown to modulate the Ras-dependent activation of Raf1; however, the mechanism underlying this effect remains elusive. Here, to characterize the role of Ca(2+) in Ras signaling to Raf1, we used a...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836960/ https://www.ncbi.nlm.nih.gov/pubmed/20071468 http://dx.doi.org/10.1091/mbc.E09-06-0455 |