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Ras and Calcium Signaling Pathways Converge at Raf1 via the Shoc2 Scaffold Protein

Situated downstream of Ras is a key signaling molecule, Raf1. Increase in Ca(2+) concentration has been shown to modulate the Ras-dependent activation of Raf1; however, the mechanism underlying this effect remains elusive. Here, to characterize the role of Ca(2+) in Ras signaling to Raf1, we used a...

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Detalles Bibliográficos
Autores principales: Yoshiki, Sayaka, Matsunaga-Udagawa, Rie, Aoki, Kazuhiro, Kamioka, Yuji, Kiyokawa, Etsuko, Matsuda, Michiyuki
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836960/
https://www.ncbi.nlm.nih.gov/pubmed/20071468
http://dx.doi.org/10.1091/mbc.E09-06-0455