Transforming Growth Factor-β1 Induces Transdifferentiation of Myoblasts into Myofibroblasts via Up-Regulation of Sphingosine Kinase-1/S1P(3) Axis

The pleiotropic cytokine transforming growth factor (TGF)-β1 is a key player in the onset of skeletal muscle fibrosis, which hampers tissue repair. However, the molecular mechanisms implicated in TGFβ1-dependent transdifferentiation of myoblasts into myofibroblasts are presently unknown. Here, we sh...

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Detalles Bibliográficos
Autores principales: Cencetti, Francesca, Bernacchioni, Caterina, Nincheri, Paola, Donati, Chiara, Bruni, Paola
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836962/
https://www.ncbi.nlm.nih.gov/pubmed/20089836
http://dx.doi.org/10.1091/mbc.E09-09-0812

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836962/
https://www.ncbi.nlm.nih.gov/pubmed/20089836
http://dx.doi.org/10.1091/mbc.E09-09-0812

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